Pharm MOD 1 Discussion Group 1 During clinical, you are charge to care for a client receiving morphine IV for affirm of postoperative pain. The clinical instructor has assigned you to explain the followers: A) What are the major differences between narcotising agonists, depressant agonists-antagonists, and narcotizing antagonists? Narcotic agonists are drugs that fight back with the opioid receptors throughout the body to piss analgesia, sedation, or euphoria. These drugs are highly addictive (p. 408). Narcotic agonists-antagonists react with some opioid receptor sites to stimulate bodily process and block opposite opioid receptor sites. These drugs are not as addictive as pure narcotic agonists (p. 414). Narcotic antagonists, which micturate to reverse the effectuate of narcotics, are used to treat narcotic overdose or to reverse unacceptable unbecoming effectuate (p. 417). B) Describe the cure actions, indications, contraindications, the mos t common adverse reactions, and master(prenominal) drug-drug interactions for a narcotic. The narcotic agonist act at special opioid receptor sites in the CNS to bring analgesia, sedation, and a moxie of well-being. They also are used as antitussives and as adjuncts to command anesthesia to produce rapid analgesia, sedation, and respiratory natural depression.
Indications for narcotic agonists include relief of exhausting acute or continuing pain, preoperative medication, analgesia during anesthesia, and specific somebody indications, depending on the receptor family relationship (p. 409). Narcotic agonists a re contraindicated in the following conditio! ns: presence of cognise all(prenominal)ergy to any narcotic agonist to avoid hypersensitivity reactions; looseness caused by toxic poisons because depression of GI occupation could petabyte to increased absorption and perniciousness; and after biliary operating room or surgical anastomoses because of the adverse effects associated with slowed GI activity due to narcotics. Oxycodone is classified as pregnancy category B, whereas all of the other...
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